Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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Sotirios Fortis

TitlePost-Doctoral Fellow
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-BioChem&Molecular Genetics

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Fortis SP, Dryllis G, Anastasiadi AT, Tzounakas VL, Konstantakopoulou O, Georgatzakou HT, Pavlou EG, Tsantes AG, Theodorogianni V, Kosma MA, Papageorgiou EG, Stamoulis KE, Beloukas A, Politou M, Valsami S, Kriebardis AG. Unveiling the impact of the COVID-19 pandemic on blood donation patterns: A Greek perspective. Transfus Apher Sci. 2025 Jun; 64(3):104122. PMID: 40300445.
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    2. Fortis SP, Grier AL, Reisz JA, Dzieciatkowska M, Cendali FI, Kauffman V, Morton DH, D'Alessandro A. Advancing the Biochemical Understanding of Maple Syrup Urine Disease and the Impact of Liver Transplantation: A Pilot Study. J Proteome Res. 2025 Jun 06; 24(6):3088-3104. PMID: 40232068.
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    3. Drossos PV, Fortis SP, Anastasiadi AT, Pavlou EG, Tsantes AG, Spyratos GA, Papageorgiou EG, Nomikou EG, Stamoulis KE, Dryllis G, Tzounakas VL, Politou M, Valsami S, Kriebardis AG. Cold vs. Room Temperature: A Comparative Analysis of Platelet Functionality in Cold Storage. Biomedicines. 2025 Jan 27; 13(2). PMID: 40002723.
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    4. Chideriotis S, Anastasiadi AT, Tzounakas VL, Fortis SP, Kriebardis AG, Valsami S. Morphogens and Cell-Derived Structures (Exosomes and Cytonemes) as Components of the Communication Between Cells. Int J Mol Sci. 2025 Jan 21; 26(3). PMID: 39940651.
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    5. Sokou R, Gounari EA, Tsante KA, Konstantinidi A, Lampridou M, Theodoraki M, Kriebardis AG, Fortis SP, Iacovidou N, Tsantes AG. Thromboelastometry-Based Profiling of Haemostatic Alterations in Neonatal Sepsis by Causative Pathogens. Antibiotics (Basel). 2025 Jan 17; 14(1). PMID: 39858386.
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    6. Batsaki P, Fortis SP, Gritzapis AD, Razou A, Sakellaridis AC, Grouzi E, Moschandreou D, Koukourakis MI, Zoumpourlis V, Baxevanis CN, Goulielmaki M. Identification of a Novel Immune-Gene Signature with Prognostic Value in Patients with Head and Neck Cancer: A Pilot Study. Biochem Genet. 2025 Jan 08. PMID: 39779579.
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    7. Tsantes AG, Domouchtsidou A, Tsante KA, Ioannou P, Mpakosi A, Petrou E, Goumenos S, Trikoupis IG, Roustemis AG, Fortis SP, Koutserimpas C, Papagelopoulos PJ, Samonis G, Bonovas S, Papadopoulos DV. Diagnostic Accuracy of Rotational Thromboelastometry for Low-Virulence Periprosthetic Joint Infections: A Pilot Study. Microorganisms. 2024 Aug 22; 12(8). PMID: 39203582.
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    8. Petrou E, Tsalas S, Tsantes AG, Loukopoulou E, Mellou S, Fortis SP, Rapti E, Sokou R, Kyriakou E, Douramani P, Frantzeskaki F, Samonis G, Kokoris S, Kriebardis A, Tsantes AE. Assessment of metabolic and hemostatic profile of apheresis platelet concentrates: does the storage medium play a role? Blood Transfus. 2024 Nov; 22(6):492-501. PMID: 39133624.
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    9. Xagara A, Goulielmaki M, Fortis SP, Kokkalis A, Chantzara E, Christodoulopoulos G, Samaras I, Saloustros E, Tsapakidis K, Papadopoulos V, Pateras IS, Georgoulias V, Baxevanis CN, Kotsakis A. Pre-Existing Immunity Predicts Response to First-Line Immunotherapy in Non-Small Cell Lung Cancer Patients. Cancers (Basel). 2024 Jun 28; 16(13). PMID: 39001455.
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    10. Tsantes AG, Petrou E, Tsante KA, Sokou R, Frantzeskaki F, Domouchtsidou A, Chaldoupis AE, Fortis SP, Piovani D, Nikolopoulos GK, Iacovidou N, Bonovas S, Samonis G, Tsantes AE. Cancer-Associated Thrombosis: Pathophysiology, Laboratory Assessment, and Current Guidelines. Cancers (Basel). 2024 May 30; 16(11). PMID: 38893201.
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    11. Kriebardis AG, Chardalias L, Damaskos C, Pouliakis A, Garmpis N, Fortis SP, Papailia A, Sideri C, Georgatzakou HT, Papageorgiou EG, Pittaras T, Tsourouflis G, Politou M, Papaconstantinou I, Dimitroulis D, Valsami S. Precision Oncology: Circulating Microvesicles as New Biomarkers in a Very Early Stage of Colorectal Cancer. Cancers (Basel). 2024 May 20; 16(10). PMID: 38792021.
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    12. Melachroinou K, Divolis G, Tsafaras G, Karampetsou M, Fortis S, Stratoulias Y, Papadopoulou G, Kriebardis AG, Samiotaki M, Vekrellis K. Endogenous Alpha-Synuclein is Essential for the Transfer of Pathology by Exosome-Enriched Extracellular Vesicles, Following Inoculation with Preformed Fibrils in vivo. Aging Dis. 2024 Apr 01; 15(2):869-892. PMID: 37548944.
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    13. Trifylli EM, Kriebardis AG, Koustas E, Papadopoulos N, Fortis SP, Tzounakas VL, Anastasiadi AT, Sarantis P, Vasileiadi S, Tsagarakis A, Aloizos G, Manolakopoulos S, Deutsch M. A Current Synopsis of the Emerging Role of Extracellular Vesicles and Micro-RNAs in Pancreatic Cancer: A Forward-Looking Plan for Diagnosis and Treatment. Int J Mol Sci. 2024 Mar 17; 25(6). PMID: 38542378.
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    14. Tsalas S, Tsantes AG, Petrou E, Mellou S, Sokou R, Loukopoulou E, Kriebardis AG, Fortis SP, Papadopoulos DV, Vaiopoulos AG, Kokoris S, Tsantes AE. The effects of pathogen reduction technology on apheresis platelet concentrates stored in PAS. Blood Transfus. 2024 Sep; 22(5):405-414. PMID: 38315533.
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    15. Giannaki A, Georgatzakou H?, Fortis SP, Anastasiadi AT, Pavlou EG, Nomikou EG, Drandaki MP, Kotsiafti A, Xydaki A, Fountzoula C, Papageorgiou EG, Tzounakas VL, Kriebardis AG. Stratification of ?S?+ Compound Heterozygotes Based on L-Glutamine Administration and RDW: Focusing on Disease Severity. Antioxidants (Basel). 2023 Nov 08; 12(11). PMID: 38001835.
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    16. Fortis SP, Batrinou A, Georgatzakou HT, Tsamesidis I, Alvanidis G, Papageorgiou EG, Stamoulis K, Gkiliopoulos D, Pouroutzidou GK, Theocharidou A, Kontonasaki E, Kriebardis AG. Effect of silica-based mesoporous nanomaterials on human blood cells. Chem Biol Interact. 2024 Jan 05; 387:110784. PMID: 37939894.
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    17. Trifylli EM, Kriebardis AG, Koustas E, Papadopoulos N, Vasileiadi S, Fortis SP, Tzounakas VL, Anastasiadi AT, Sarantis P, Papageorgiou EG, Tsagarakis A, Aloizos G, Manolakopoulos S, Deutsch M. The Arising Role of Extracellular Vesicles in Cholangiocarcinoma: A Rundown of the Current Knowledge Regarding Diagnostic and Therapeutic Approaches. Int J Mol Sci. 2023 Oct 25; 24(21). PMID: 37958547.
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    18. Koukourakis MI, Xanthopoulou E, Koukourakis IM, Fortis SP, Kesesidis N, Kakouratos C, Karakasiliotis I, Baxevanis CN. Next-Generation Sequencing Analysis of Mutations in Circulating Tumor DNA from the Plasma of Patients with Head-Neck Cancer Undergoing Chemo-Radiotherapy Using a Pan-Cancer Cell-Free Assay. Curr Oncol. 2023 09 29; 30(10):8902-8915. PMID: 37887543.
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    19. Stokidis S, Baxevanis CN, Fortis SP. The Prognostic Significance of Selected HLA Alleles on Prostate Cancer Outcome. Int J Mol Sci. 2023 Sep 22; 24(19). PMID: 37833904.
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    20. Koukourakis MI, Xanthopoulou E, Koukourakis IM, Fortis SP, Kesesidis N, Karakasiliotis I, Baxevanis CN. Circulating Plasma Cell-free DNA (cfDNA) as a Predictive Biomarker for Radiotherapy: Results from a Prospective Trial in Head and Neck Cancer. Cancer Diagn Progn. 2023 Sep-Oct; 3(5):551-557. PMID: 37671311.
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    21. Fortis SP, Batsaki P, Stokidis S, Moschandreou D, Grouzi E, Baxevanis CN, Gritzapis AD, Goulielmaki M. A Blood-Based Immune Gene Signature with Prognostic Significance in Localized Prostate Cancer. Cancers (Basel). 2023 Jul 20; 15(14). PMID: 37509358.
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    22. Kogionou P, Fortis SP, Goulielmaki M, Aubert N, Batsaki P, Ouzounis S, Cavouras D, Marodon G, Stokidis S, Gritzapis AD, Baxevanis CN. Correction: Kogionou et al. Radiotherapy-Related Gene Signature in Prostate Cancer. Cancers 2022, 14, 5032. Cancers (Basel). 2023 Jul 14; 15(14). PMID: 37509413.
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    23. Pavlidis G, Giannoulis V, Pirounaki M, Lampropoulos IC, Siafi E, Nitsa A, Pavlou E, Xanthaki A, Perlepe G, Fortis SP, Charalambous G, Kampolis CF, Pantazopoulos I. Evaluation of Antibody Kinetics Following COVID-19 Vaccination in Greek SARS-CoV-2 Infected and Na?ve Healthcare Workers. J Pers Med. 2023 May 29; 13(6). PMID: 37373899.
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    24. Goulielmaki M, Stokidis S, Anagnostou T, Voutsas IF, Gritzapis AD, Baxevanis CN, Fortis SP. Frequencies of an Immunogenic HER-2/neu Epitope of CD8+ T Lymphocytes Predict Favorable Clinical Outcomes in Prostate Cancer. Int J Mol Sci. 2023 Mar 22; 24(6). PMID: 36983028.
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    25. Papalouka C, Adamaki M, Batsaki P, Zoumpourlis P, Tsintarakis A, Goulielmaki M, Fortis SP, Baxevanis CN, Zoumpourlis V. DNA Damage Response Mechanisms in Head and Neck Cancer: Significant Implications for Therapy and Survival. Int J Mol Sci. 2023 Feb 01; 24(3). PMID: 36769087.
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    26. Fortis SP, Sofopoulos M, Goulielmaki M, Arnogiannaki N, Ardavanis A, Perez SA, Gritzapis AD, Baxevanis CN. Association between Intratumoral CD8+ T Cells with FoxP3+ and CD163+ Cells: A Potential Immune Intrinsic Negative Feedback Mechanism for Acquired Immune Resistance. Cancers (Basel). 2022 Dec 15; 14(24). PMID: 36551693.
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    27. Baxevanis CN, Goulielmaki M, Gritzapis AD, Fortis SP. Combination Immunotherapy in Prostate Cancer. Cancers (Basel). 2022 Dec 08; 14(24). PMID: 36551526.
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    28. Zamanakou M, Vatsiou S, Batsaki P, Fortis SP, Germenis AE. Identification of the novel HLA-DRB1*11:308 allele in a Greek individual. HLA. 2023 05; 101(5):555-557. PMID: 36437488.
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    29. Baxevanis CN, Goulielmaki M, Adamaki M, Fortis SP. The thin red line between the immune system and cancer evolution. Transl Oncol. 2023 Jan; 27:101555. PMID: 36265329.
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    30. Fortis SP, Goulielmaki M, Aubert N, Batsaki P, Ouzounis S, Cavouras D, Marodon G, Stokidis S, Gritzapis AD, Baxevanis CN. Radiotherapy-Related Gene Signature in Prostate Cancer. Cancers (Basel). 2022 Oct 14; 14(20). PMID: 36291815.
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    31. Trifylli EM, Kriebardis AG, Koustas E, Papadopoulos N, Deutsch M, Aloizos G, Fortis SP, Papageorgiou EG, Tsagarakis A, Manolakopoulos S. The Emerging Role of Extracellular Vesicles and Autophagy Machinery in NASH-Future Horizons in NASH Management. Int J Mol Sci. 2022 Oct 12; 23(20). PMID: 36293042.
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    32. Thomaidou AC, Batsaki P, Adamaki M, Goulielmaki M, Baxevanis CN, Zoumpourlis V, Fortis SP. Promising Biomarkers in Head and Neck Cancer: The Most Clinically Important miRNAs. Int J Mol Sci. 2022 Jul 26; 23(15). PMID: 35897831.
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    33. Georgatzakou HT, Fortis SP, Papageorgiou EG, Antonelou MH, Kriebardis AG. Blood Cell-Derived Microvesicles in Hematological Diseases and beyond. Biomolecules. 2022 06 08; 12(6). PMID: 35740926.
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    34. Baxevanis CN, Gritzapis AD, Voutsas IF, Batsaki P, Goulielmaki M, Adamaki M, Zoumpourlis V, Fortis SP. T-Cell Repertoire in Tumor Radiation: The Emerging Frontier as a Radiotherapy Biomarker. Cancers (Basel). 2022 May 27; 14(11). PMID: 35681654.
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    35. Fortis SP, Kriebardis AG, Georgatzakou HT, Lyrakos G, Alexiou P, Antoniou C, Papadopoulos G, Stamoulis KE, Valsami S. Economic crisis in Greece: The invisible enemy of blood donation or not? Transfus Apher Sci. 2022 Dec; 61(6):103467. PMID: 35623957.
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    36. Goulielmaki M, Davanos N, Kogionou P, Batsaki P, Stokidis S, Adamaki M, Mosa E, Vasilakou E, Zambatis C, Gritzapis AD, Zoumpourlis V, Baxevanis CN, Fortis SP. The impact of radiation therapy on the TCR V? chain repertoire in patients with prostate cancer. Int J Oncol. 2022 Jun; 60(6). PMID: 35445738.
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    37. Bouchla A, Kriebardis AG, Georgatzakou HT, Fortis SP, Thomopoulos TP, Lekkakou L, Markakis K, Gkotzias D, Panagiotou A, Papageorgiou EG, Pouliakis A, Stamoulis KE, Papageorgiou SG, Pappa V, Valsami S. Red Blood Cell Abnormalities as the Mirror of SARS-CoV-2 Disease Severity: A Pilot Study. Front Physiol. 2021; 12:825055. PMID: 35126186.
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    38. Pavlou EG, Georgatzakou HT, Fortis SP, Tsante KA, Tsantes AG, Nomikou EG, Kapota AI, Petras DI, Venetikou MS, Papageorgiou EG, Antonelou MH, Kriebardis AG. Coagulation Abnormalities in Renal Pathology of Chronic Kidney Disease: The Interplay between Blood Cells and Soluble Factors. Biomolecules. 2021 09 04; 11(9). PMID: 34572522.
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    39. Zamanakou M, Vatsiou S, Stokidis S, Fortis SP, Germenis AE. Identification of two novel alleles, HLA-A*02:01:193 and -DQA1*02:17, in Greek individuals. HLA. 2021 06; 97(6):521-523. PMID: 33608989.
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    40. Ioannidou K, Ndiaye DR, Noto A, Fenwick C, Fortis SP, Pantaleo G, Petrovas C, de Leval L. In Situ Characterization of Follicular Helper CD4 T Cells Using Multiplexed Imaging. Front Immunol. 2020; 11:607626. PMID: 33633728.
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    41. Baxevanis CN, Fortis SP, Ardavanis A, Perez SA. Exploring Essential Issues for Improving Therapeutic Cancer Vaccine Trial Design. Cancers (Basel). 2020 Oct 10; 12(10). PMID: 33050520.
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    42. Stokidis S, Fortis SP, Kogionou P, Anagnostou T, Perez SA, Baxevanis CN. HLA Class I Allele Expression and Clinical Outcome in De Novo Metastatic Prostate Cancer. Cancers (Basel). 2020 Jun 18; 12(6). PMID: 32570992.
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    43. Baxevanis CN, Fortis SP, Perez SA. The balance between breast cancer and the immune system: Challenges for prognosis and clinical benefit from immunotherapies. Semin Cancer Biol. 2021 07; 72:76-89. PMID: 31881337.
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    44. Sofopoulos M, Fortis SP, Vaxevanis CK, Sotiriadou NN, Arnogiannaki N, Ardavanis A, Vlachodimitropoulos D, Perez SA, Baxevanis CN. The prognostic significance of peritumoral tertiary lymphoid structures in breast cancer. Cancer Immunol Immunother. 2019 Nov; 68(11):1733-1745. PMID: 31598757.
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    45. Fortis SP, Kotsakis A, Le Tourneau C, Tsitsilonis OE, Georgoulias V, Baxevanis CN. 4th Symposium on Advances in Cancer Immunology and Immunotherapy, November 29-December 1, 2018, Athens, Greece. Cancer Immunol Immunother. 2019 08; 68(8):1391-1400. PMID: 31309256.
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    46. Baxevanis CN, Sofopoulos M, Fortis SP, Perez SA. The role of immune infiltrates as prognostic biomarkers in patients with breast cancer. Cancer Immunol Immunother. 2019 Oct; 68(10):1671-1680. PMID: 30905043.
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    47. Baxevanis CN, Fortis SP, Perez SA. Prostate cancer: any room left for immunotherapies? Immunotherapy. 2019 02; 11(2):69-74. PMID: 30727800.
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    48. Watson DC, Moysi E, Valentin A, Bergamaschi C, Devasundaram S, Fortis SP, Bear J, Chertova E, Bess J, Sowder R, Venzon DJ, Deleage C, Estes JD, Lifson JD, Petrovas C, Felber BK, Pavlakis GN. Correction: Treatment with native heterodimeric IL-15 increases cytotoxic lymphocytes and reduces SHIV RNA in lymph nodes. PLoS Pathog. 2018 10; 14(10):e1007345. PMID: 30308061.
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    49. Fortis SP, Vaxevanis CK, Mahaira LG, Sofopoulos M, Sotiriadou NN, Dinou A, Arnogiannaki N, Stavropoulos-Giokas C, Thanos D, Baxevanis CN, Perez SA. Serum miRNA-based distinct clusters define three groups of breast cancer patients with different clinicopathological and immune characteristics. Cancer Immunol Immunother. 2019 Jan; 68(1):57-70. PMID: 30276443.
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    50. Watson DC, Moysi E, Valentin A, Bergamaschi C, Devasundaram S, Fortis SP, Bear J, Chertova E, Bess J, Sowder R, Venzon DJ, Deleage C, Estes JD, Lifson JD, Petrovas C, Felber BK, Pavlakis GN. Treatment with native heterodimeric IL-15 increases cytotoxic lymphocytes and reduces SHIV RNA in lymph nodes. PLoS Pathog. 2018 02; 14(2):e1006902. PMID: 29474450.
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    51. Fortis SP, Mahaira LG, Anastasopoulou EA, Voutsas IF, Perez SA, Baxevanis CN. Immune profiling of melanoma tumors reflecting aggressiveness in a preclinical model. Cancer Immunol Immunother. 2017 Dec; 66(12):1631-1642. PMID: 28871365.
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    52. Fortis SP, Sofopoulos M, Sotiriadou NN, Haritos C, Vaxevanis CK, Anastasopoulou EA, Janssen N, Arnogiannaki N, Ardavanis A, Pawelec G, Perez SA, Baxevanis CN. Erratum to: Differential intratumoral distributions of CD8 and CD163 immune cells as prognostic biomarkers in breast cancer. J Immunother Cancer. 2017; 5:48. PMID: 28572978.
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    53. Fortis SP, Sofopoulos M, Sotiriadou NN, Haritos C, Vaxevanis CK, Anastasopoulou EA, Janssen N, Arnogiannaki N, Ardavanis A, Pawelec G, Perez SA, Baxevanis CN. Differential intratumoral distributions of CD8 and CD163 immune cells as prognostic biomarkers in breast cancer. J Immunother Cancer. 2017; 5:39. PMID: 28428887.
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    54. Fortis SP, Anastasopoulou EA, Voutsas IF, Baxevanis CN, Perez SA, Mahaira LG. Potential Prognostic Molecular Signatures in a Preclinical Model of Melanoma. Anticancer Res. 2017 01; 37(1):143-148. PMID: 28011484.
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    55. Janssen N, Fortis SP, Speigl L, Haritos C, Sotiriadou NN, Sofopoulos M, Arnogiannaki N, Stavropoulos-Giokas C, Dinou A, Perez S, Pawelec G, Baxevanis CN, Shipp C. Peripheral T cell responses to tumour antigens are associated with molecular, immunogenetic and cellular features of breast cancer patients. Breast Cancer Res Treat. 2017 01; 161(1):51-62. PMID: 27787640.
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    56. Mahaira LG, Katsara O, Pappou E, Iliopoulou EG, Fortis S, Antsaklis A, Fotinopoulos P, Baxevanis CN, Papamichail M, Perez SA. IGF2BP1 expression in human mesenchymal stem cells significantly affects their proliferation and is under the epigenetic control of TET1/2 demethylases. Stem Cells Dev. 2014 Oct 15; 23(20):2501-12. PMID: 24915579.
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