Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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Last Name
Institution

Laura K. Wiley

TitleAssociate Professor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-BIOMED Informatics Gen Ops
Phone303/724-0319

    Collapse Research 
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    K01LM013088     (WILEY, LAURA KATHERINE)May 17, 2019 - Apr 30, 2022
    NIH
    Clinical Evidence Generation from Electronic Health Records for Precision Medicine
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Guo B, Cai Y, Kim D, Smit RAJ, Wang Z, Iyer KR, Hilliard AT, Haessler J, Tao R, Broadaway KA, Wang Y, Pozdeyev N, St?ger FF, Yang C, Vanderwerff B, Patki AD, Stalbow L, Lin M, Rafaels N, Shortt J, Wiley L, Stanislawski M, Pattee J, Davis L, Straub PS, Shuey MM, Cox NJ, Lee NR, J?rgensen ME, Bjerregaard P, Larsen C, Hansen T, Moltke I, Meigs JB, Stram DO, Yin X, Zhou X, Chang KM, Clarke SL, Guarischi-Sousa R, Lankester J, Tsao PS, Buyske S, Graff M, Raffield LM, Sun Q, Wilkens LR, Carlson CS, Easton CB, Liu S, Manson JE, Marchand LL, Haiman CA, Mohlke KL, Gordon-Larsen P, Albrechtsen A, Boehnke M, Rich SS, Manichaikul A, Rotter JI, Yousri NA, Irvin RM, Gignoux C, North KE, Loos RJF, Assimes TL, Peters U, Kooperberg C, Raghavan S, Highland HM, Darst BF. Type 2 diabetes polygenic risk score demonstrates context-dependent effects and associations with type 2 diabetes-related risk factors and complications across diverse populations. medRxiv. 2025 Feb 20. PMID: 40034751.
      View in: PubMed
    2. Liu H, Abedini A, Ha E, Ma Z, Sheng X, Dumoulin B, Qiu C, Aranyi T, Li S, Dittrich N, Chen HC, Tao R, Tarng DC, Hsieh FJ, Chen SA, Yang SF, Lee MY, Kwok PY, Wu JY, Chen CH, Khan A, Limdi NA, Wei WQ, Walunas TL, Karlson EW, Kenny EE, Luo Y, Kottyan L, Connolly JJ, Jarvik GP, Weng C, Shang N, Cole JB, Mercader JM, Mandla R, Majarian TD, Florez JC, Haas ME, Lotta LA, Drivas TG, Vy HMT, Nadkarni GN, Wiley LK, Wilson MP, Gignoux CR, Rasheed H, Thomas LF, ?svold BO, Brumpton BM, Hallan SI, Hveem K, Zheng J, Hellwege JN, Zawistowski M, Z?llner S, Franceschini N, Hu H, Zhou J, Kiryluk K, Ritchie MD, Palmer M, Edwards TL, Voight BF, Hung AM, Susztak K. Kidney multiome-based genetic scorecard reveals convergent coding and regulatory variants. Science. 2025 Feb 07; 387(6734):eadp4753. PMID: 39913582.
      View in: PubMed
    3. Holland MA, Maisel K, Ibberson CB, Wiley LK, Burnett DC, Mace EM, Elting MW. Extended time, elevated expectations: The unappreciated downsides of pausing the tenure clock. Proc Natl Acad Sci U S A. 2024 Aug 20; 121(34):e2403489121. PMID: 39150787.
      View in: PubMed
    4. Thornton WA, Smulligan K, Weber KA, Tefertiller C, Ma?ago M, Sevigny M, Wiley L, Stevens-Lapsley J, Smith AC. Lesion characteristics are associated with bowel, bladder, and overall independence following cervical spinal cord injury. J Spinal Cord Med. 2024 Jul 03; 1-9. PMID: 38958637.
      View in: PubMed
    5. Hoffman JE, Morel B, Wittenberg B, Kumpe D, Seinfeld J, Folzenlogen Z, Case D, Neumann R, Cava L, Breeze R, Wiley L, Roark C. Periprocedural management of ruptured blister aneurysms treated with pipeline flow diversion. Surg Neurol Int. 2024; 15:73. PMID: 38628521.
      View in: PubMed
    6. Wiley LK, Shortt JA, Roberts ER, Lowery J, Kudron E, Lin M, Mayer D, Wilson M, Brunetti TM, Chavan S, Phang TL, Pozdeyev N, Lesny J, Wicks SJ, Moore ET, Morgenstern JL, Roff AN, Shalowitz EL, Stewart A, Williams C, Edelmann MN, Hull M, Patton JT, Axell L, Ku L, Lee YM, Jirikowic J, Tanaka A, Todd E, White S, Peterson B, Hearst E, Zane R, Greene CS, Mathias R, Coors M, Taylor M, Ghosh D, Kahn MG, Brooks IM, Aquilante CL, Kao D, Rafaels N, Crooks KR, Hess S, Barnes KC, Gignoux CR. Building a vertically integrated genomic learning health system: The biobank at the Colorado Center for Personalized Medicine. Am J Hum Genet. 2024 01 04; 111(1):11-23. PMID: 38181729.
      View in: PubMed
    7. Brandt PS, Kho A, Luo Y, Pacheco JA, Walunas TL, Hakonarson H, Hripcsak G, Liu C, Shang N, Weng C, Walton N, Carrell DS, Crane PK, Larson EB, Chute CG, Kullo IJ, Carroll R, Denny J, Ramirez A, Wei WQ, Pathak J, Wiley LK, Richesson R, Starren JB, Rasmussen LV. Characterizing variability of electronic health record-driven phenotype definitions. J Am Med Inform Assoc. 2023 02 16; 30(3):427-437. PMID: 36474423.
      View in: PubMed
    8. Mayer DA, Rasmussen LV, Roark CD, Kahn MG, Schilling LM, Wiley LK. ReviewR: a light-weight and extensible tool for manual review of clinical records. JAMIA Open. 2022 Oct; 5(3):ooac071. PMID: 35936991.
      View in: PubMed
    9. Pfaff ER, Girvin AT, Gabriel DL, Kostka K, Morris M, Palchuk MB, Lehmann HP, Amor B, Bissell M, Bradwell KR, Gold S, Hong SS, Loomba J, Manna A, McMurry JA, Niehaus E, Qureshi N, Walden A, Zhang XT, Zhu RL, Moffitt RA, Haendel MA, Chute CG, Adams WG, Al-Shukri S, Anzalone A, Baghal A, Bennett TD, Bernstam EV, Bernstam EV, Bissell MM, Bush B, Campion TR, Castro V, Chang J, Chaudhari DD, Chen W, Chu S, Cimino JJ, Crandall KA, Crooks M, Davies SJD, DiPalazzo J, Dorr D, Eckrich D, Eltinge SE, Fort DG, Golovko G, Gupta S, Haendel MA, Hajagos JG, Hanauer DA, Harnett BM, Horswell R, Huang N, Johnson SG, Kahn M, Khanipov K, Kieler C, Luzuriaga KR, Maidlow S, Martinez A, Mathew J, McClay JC, McMahan G, Melancon B, Meystre S, Miele L, Morizono H, Pablo R, Patel L, Phuong J, Popham DJ, Pulgarin C, Santos C, Sarkar IN, Sazo N, Setoguchi S, Soby S, Surampalli S, Suver C, Vangala UMR, Visweswaran S, Oehsen JV, Walters KM, Wiley L, Williams DA, Zai A. Synergies between centralized and federated approaches to data quality: a report from the national COVID cohort collaborative. J Am Med Inform Assoc. 2022 03 15; 29(4):609-618. PMID: 34590684.
      View in: PubMed
    10. Mayer D, Russell S, Wilson MP, Kahn MG, Wiley LK. Developing and Deploying a Scalable Computing Platform to Support MOOC Education in Clinical Data Science. AMIA Jt Summits Transl Sci Proc. 2021; 2021:430-437. PMID: 34457158.
      View in: PubMed
    11. Hicks JK, El Rouby N, Ong HH, Schildcrout JS, Ramsey LB, Shi Y, Anne Tang L, Aquilante CL, Beitelshees AL, Blake KV, Cimino JJ, Davis BH, Empey PE, Kao DP, Lemkin DL, Limdi NA, P Lipori G, Rosenman MB, Skaar TC, Teal E, Tuteja S, Wiley LK, Williams H, Winterstein AG, Van Driest SL, Cavallari LH, Peterson JF. Opportunity for Genotype-Guided Prescribing Among Adult Patients in 11 US Health Systems. Clin Pharmacol Ther. 2021 07; 110(1):179-188. PMID: 33428770.
      View in: PubMed
    12. Roark C, Wilson MP, Kubes S, Mayer D, Wiley LK. Assessing the utility and accuracy of ICD10-CM non-traumatic subarachnoid hemorrhage codes for intracranial aneurysm research. Learn Health Syst. 2021 Oct; 5(4):e10257. PMID: 34667877.
      View in: PubMed
    13. Seligson ND, Warner JL, Dalton WS, Martin D, Miller RS, Patt D, Kehl KL, Palchuk MB, Alterovitz G, Wiley LK, Huang M, Shen F, Wang Y, Nguyen KA, Wong AF, Meric-Bernstam F, Bernstam EV, Chen JL. Recommendations for patient similarity classes: results of the AMIA 2019 workshop on defining patient similarity. J Am Med Inform Assoc. 2020 11 01; 27(11):1808-1812. PMID: 32885823.
      View in: PubMed
    14. Roark CD, Beseler C, Wiley LK, Case D, Folzenlogen Z, Hosokawa P, Seinfeld J. Predictors of 90-Day Readmission Rate After Unruptured Intracranial Aneurysm Repair. World Neurosurg. 2020 09; 141:e728-e735. PMID: 32525089.
      View in: PubMed
    15. Ching T, Himmelstein DS, Beaulieu-Jones BK, Kalinin AA, Do BT, Way GP, Ferrero E, Agapow PM, Zietz M, Hoffman MM, Xie W, Rosen GL, Lengerich BJ, Israeli J, Lanchantin J, Woloszynek S, Carpenter AE, Shrikumar A, Xu J, Cofer EM, Lavender CA, Turaga SC, Alexandari AM, Lu Z, Harris DJ, DeCaprio D, Qi Y, Kundaje A, Peng Y, Wiley LK, Segler MHS, Boca SM, Swamidass SJ, Huang A, Gitter A, Greene CS. Opportunities and obstacles for deep learning in biology and medicine. J R Soc Interface. 2018 04; 15(141). PMID: 29618526.
      View in: PubMed
    16. Southerland WM, Swamidass SJ, Payne PRO, Wiley L, Williams-DeVane C. The diversity and disparity in biomedical informatics (DDBI) workshop. Pac Symp Biocomput. 2018; 23:614-617. PMID: 29218919.
      View in: PubMed
    17. Wiley LK, Vanhouten JP, Samuels DC, Aldrich MC, Roden DM, Peterson JF, Denny JC. STRATEGIES FOR EQUITABLE PHARMACOGENOMIC-GUIDED WARFARIN DOSING AMONG EUROPEAN AND AFRICAN AMERICAN INDIVIDUALS IN A CLINICAL POPULATION. Pac Symp Biocomput. 2017; 22:545-556. PMID: 27897005.
      View in: PubMed
    18. Wiley LK, Tarczy-Hornoch P, Denny JC, Freimuth RR, Overby CL, Shah N, Martin RD, Sarkar IN. Harnessing next-generation informatics for personalizing medicine: a report from AMIA's 2014 Health Policy Invitational Meeting. J Am Med Inform Assoc. 2016 Mar; 23(2):413-9. PMID: 26911808.
      View in: PubMed
    19. Wiley LK, Moretz JD, Denny JC, Peterson JF, Bush WS. Phenotyping Adverse Drug Reactions: Statin-Related Myotoxicity. AMIA Jt Summits Transl Sci Proc. 2015; 2015:466-70. PMID: 26306287.
      View in: PubMed
    20. Wiley LK, Sivley RM, Bush WS. Rapid storage and retrieval of genomic intervals from a relational database system using nested containment lists. Database (Oxford). 2013; 2013:bat056. PMID: 23894185.
      View in: PubMed
    21. Wiley LK, Shah A, Xu H, Bush WS. ICD-9 tobacco use codes are effective identifiers of smoking status. J Am Med Inform Assoc. 2013 Jul-Aug; 20(4):652-8. PMID: 23396545.
      View in: PubMed
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